An inherited bleeding disorder that involves the improper clotting of blood can best be described as what’s hemophilia. This health condition can lead to involuntary bleeding as well as bleeding due to surgery or injuries.
Hemophilia in children is a bleeding disorder that is normally passed onto boys from their mothers via the X chromosome though this health condition can also arise without any family history or attachment.
Is Hemophilia genetic?
Just as previously mentioned in this article, children can easily get the hemophilia gene from their parents especially mothers. The answer to the above question is YES.
Let’s take a cursory look at the carrier of the hemophilia gene.
Any woman who carries the gene of mutation with or without showing any symptoms of Hemophilia is known as carrier of Hemophilia. Such a woman easily passes the problem to her kids.Also note that carriers usually bleed longer than what is obtainable with a normal person, who is not a carrier.
There are many ways the hemophilia gene can be passed on. Here is the first situation. If a man that has hemophilia is with a woman that is not a carrier, none of their male children will have the gene due to the fact that the father passes along his normal Y chromosome and the mother passes on her usual X chromosome. But, all of their female children would be carriers.
Let’s now take a look at three ways through which a girl can be born with a severe hemophilia gene (these scenarios are always scarce):
- A woman that is a carrier has a child with a man that is not carrying an hemophilia gene and a second new instinctive hemophilia mutation occurs when the child is born.
- A man that has the gene has a child with a woman who is not a carrier and a second new instinctive hemophilia mutation occurs during the birth of the child.
- A man who has the hemophilia gene has a child with a woman that is a carrier and together they both pass the mutated X chromosome to the child when she is born.
The second situation goes thus. If a woman who is a carrier has a son with a man that has no hemophilia gene, the son has an equal chance (50/50) of developing hemophilia or not while the daughter has an equal chance (50/50) of being a carrier despite not developing the gene if they give birth to a female child.
Next, we want to examine why children with no history of hemophilia record the condition. There are two reasons why this is possible.
- An ‘instinctive’ genetic mutation: Some hemophilia gene cases arise from a new or ‘instinctive’ genetic mutation meaning a genetic issue occurs without any known reason and this could take place in the mother at the time of conception or in the child during conception.
- An unknown family history: It is likely that the hemophilia gene was in the family for a very long time before but went unnoticed since no son that has the condition was born in a long while.
Causes of hemophilia
The causes of hemophilia can be traced to a gene or mutation, in one of the genes, that gives orders as regard the making of clotting factor proteins that are responsible for blood clotting.
Symptoms of hemophilia
Symptoms of hemophilia include bleeding into the skin, bleeding after circumcision, frequent or hard-to-stop nosebleeds, bleeding into the joint, bleeding after vaccinations, bleeding of the mouth and gums, as well as bleeding in the head of an infant after a hard child delivery.
Effects of hemophilia
Effects of hemophilia include – Bleeding in the head and the brain (on some occasions) thus leading to long term health conditions such as paralysis and seizures.
- Bleeding within joints thus leading to chronic joint pain and disease.
- Death resulting from failure to stop bleeding or bleeding in vital organs such as the brain.
Treatment Options for of hemophilia
One of the most effective treatment options for hemophilia is by replacing the missing blood clotting factor for the blood to clot properly and this can be achieved by administering commercially prepared factor concentrates through a vein. Other options include immobilization, blood transfusion, and surgery.